Diagnosis of Precirrhotic Hemochromatosis
نویسندگان
چکیده
منابع مشابه
Can Individuals with Latent (Precirrhotic) Hemochromatosis be Accepted at Standard Rates?
A rational evaluation by insurance medical directors of an applicant for life or health insurance requires not only adequate information from a prospective insuree, but current knowledge concerning a common genetic disorder such as genetic hemochromatosis (GH), and the routine use of an appropriate screening test for GH of all applicants. Such an evaluation could make a vital difference in prog...
متن کاملDiagnosis and management of hereditary hemochromatosis.
Hereditary hemochromatosis is inherited in an autosomal recessive manner with partial biochemical expression in heterozygotes. A high percentage of saturation of serum transferrin is the hallmark of the disorder, and serum ferritin concentration gives an approximate estimation of the size of iron stores. Hepatic computed tomography, magnetic susceptometry, and nuclear magnetic resonance provide...
متن کاملHereditary Hemochromatosis: Risk Factors, Classifications, Diagnosis
Hereditary hemochromatosis (HH), also termed “genetic hemochromatosis”, is a genetic autosomal recessive disorder which occurs as a result of genetic mutations of certain genes (HFE gene) involved in the metabolism of iron, resulting in increased intestinal iron absorption. Common initial symptoms comprise abdominal pain, paleness, lethargy, and weight loss. The start of symptoms is between 30 ...
متن کاملHereditary hemochromatosis: a neglected diagnosis in orthopedics
Hereditary hemochromatosis (HH) is a not uncommon auto-somal recessive and potentially life-threatening disease. The hemochromatosis gene was identified by Feder et al. in 1996. About 1 in 200 individuals is estimated to be homozygous for the most common mutation—C282Y/C282Y. In the classical form of the disease, cysteine is substituted by tyrosine at amino acid 282 in both alleles. The so-call...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1981
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(81)80093-5